
Research
Advancing Knowledge, Transforming Heart Health
Our research is driven by a commitment to tackling one of the most pressing health challenges—cardiovascular disease. Explore cutting-edge studies on the disproportionate burden of heart disease in South Asian communities, the role of early-onset risk factors, and innovations in diagnostic tools, preventive care, and cardiometabolic screening that are shaping the future of heart health.
Cardiovascular Disease in South Asians: What You Need to Know
Cardiovascular disease (CVD) refers to a range of heart and blood vessel disorders—including heart attacks, strokes, and coronary artery disease—that are leading causes of death worldwide. While CVD affects all populations, South Asians (those from India, Pakistan, Bangladesh, Sri Lanka, Nepal, and nearby regions) face a significantly elevated risk. This increased vulnerability stems from a complex interplay of genetic predisposition, unhealthy lifestyle patterns, and environmental stressors, making early prevention and targeted intervention essential.
Detecting Risk Before It Strikes
Most South Asians develop heart disease without symptoms.
We focus on identifying risk early using the most advanced, non-invasive tools available — because standard tests often miss the signs in our communities.
We specialize in early identification of cardiovascular risk through advanced imaging and biomarker diagnostics. Our clinical prevention programs emphasize the use of coronary CT angiography (CTA), calcium scoring, and other non-invasive screening modalities to detect subclinical atherosclerosis and vascular inflammation — conditions that are often missed using traditional assessment tools. These screenings are particularly vital for South Asians, who may develop high-risk plaque formations in the absence of typical risk factors like obesity or smoking. Early detection allows for timely intervention and individualized care planning.
The use of coronary CT angiography (CTA), calcium scoring, and other screening methods to detect dangerous plaque buildup before it’s too late is crucial— particularly in younger adults who might otherwise be overlooked.
Insulin Resistance: The Earliest Red Flag
Insulin resistance shows up earlier and more often in South Asians — even when weight looks normal.
We’re investigating how it progresses, how it hides, and how we can stop it before it turns into diabetes or heart disease.
We specialize in early identification of cardiovascular risk through advanced imaging and biomarker diagnostics. Our clinical prevention programs emphasize the use of coronary CT angiography (CTA), calcium scoring, and other non-invasive screening modalities to detect subclinical atherosclerosis and vascular inflammation — conditions that are often missed using traditional assessment tools. These screenings are particularly vital for South Asians, who may develop high-risk plaque formations in the absence of typical risk factors like obesity or smoking. Early detection allows for timely intervention and individualized care planning.
Our research explores how early insulin resistance behaves in South Asians and how interventions — lifestyle or clinical — can delay or prevent metabolic decline.
Visceral Fat: The Fat You Can’t See
It’s not how much fat you have — it’s where you carry it.
South Asians store more fat around vital organs, even at lower BMIs, driving inflammation and disease from the inside out.
Unlike other populations, South Asians have a disproportionate tendency to accumulate visceral fat — fat that surrounds internal organs — even when body weight appears within a “healthy” range. This form of adiposity is strongly linked to systemic inflammation, metabolic syndrome, and increased cardiometabolic risk. LPS Health is working to quantify and characterize visceral fat patterns in South Asians, with the goal of developing more accurate screening protocols and tailored interventions that reflect this hidden burden.
We study visceral adiposity patterns in South Asians to help redefine what “at-risk” really means — and ensure better screening guidelines for our population.
Lp(a): The Genetic Time Bomb
One blood marker. A lifetime of risk.
Lipoprotein(a), or Lp(a), is a powerful inherited factor for heart disease — and it's often ignored. We're changing that.
Elevated lipoprotein(a), or Lp(a), is a genetically inherited risk factor that significantly increases the likelihood of atherosclerotic cardiovascular disease. While Lp(a) is increasingly recognized in broader cardiology, its prevalence and impact in South Asian populations remain under-researched. At LPS Health, we are committed to advancing understanding of Lp(a)-associated risk in this community — including how it interacts with other metabolic and inflammatory pathways — to better inform future screening and treatment guidelines.
We’re researching how Lp(a) disproportionately affects South Asians, how it accelerates heart risk, and how we can bring it into the spotlight of routine prevention.
Take the First Step Toward Better Heart & Metabolic Health
Your health journey starts with understanding where you stand. Our simple Cardiometabolic Health Test helps you check key risk factors like blood pressure, blood sugar, and cholesterol. It’s a quick, informative way to gain insights and take proactive steps toward feeling your best—with support every step of the way.